Pharmaceutics -I Free Notes Download – B. Pharm

Unit I

Historical background and development of profession of pharmacy

History of profession of Pharmacy in India in relation to pharmacy education, industry and organization, Pharmacy as a career, Pharmacopoeias: Introduction to IP, BP, USP and Extra Pharmacopoeia.

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Dosage forms

Introduction to dosage forms, classification and definitions

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Prescription

Definition, Parts of prescription, handling of Prescription and Errors in prescription.

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Posology

Definition, Factors affecting posology. Pediatric dose calculations based on age, body weight and body surface area.

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Unit II

Pharmaceutical calculations

Weights and measures – Imperial & Metric system, Calculations involving percentage solutions, alligation, proof spirit and isotonic solutions based on freezing point and molecular weight.

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Powders

Definition, classification, advantages and disadvantages,Simple & compound powders – official preparations, dusting powders, effervescent, efflorescent and hygroscopic powders, eutectic mixtures. Geometric dilutions.

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Liquid dosage forms

Advantages and disadvantages of liquid dosage forms. Excipients used in formulation of liquid dosage forms. Solubility enhancement techniques

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Unit III

Monophasic liquids

Definitions and preparations of Gargles, Mouthwashes, Throat Paint, Eardrops, Nasal drops, Enemas, Syrups, Elixirs, Liniments and Lotions.

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Biphasic liquids

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Suspensions

Definition, advantages and disadvantages, classifications, Preparation of suspensions; Flocculated and Deflocculated suspension & stability problems and methods to overcome.

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Emulsions

Definition, classification, emulsifying agent, test for the identification of type ofEmulsion, Methods of preparation & stability problems and methods to overcome.

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Unit IV

Suppositories

Definition, types, advantages and disadvantages, types of bases, methods of preparations. Displacement value & its calculations, evaluation of suppositories.

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Pharmaceutical incompatibilities

Definition, classification, physical, chemical and therapeutic incompatibilities with examples.

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Unit V

Semisolid dosage forms

Definitions, classification, mechanisms and factors influencing dermal penetration of drugs. Preparation of ointments, pastes, creams and gels. Excipients used in semi solid dosage forms. Evaluation of semi solid dosages forms

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