Unit I

Impurities in pharmaceutical substances

History of Pharmacopoeia, Sources and types of impurities, principle involved in the limit test for Chloride, Sulphate, Iron, Arsenic, Lead and Heavy metals, modified limit test for Chloride and Sulphate
General methods of preparation, assay for the compounds superscripted with asterisk (*), properties and medicinal uses of inorganic compounds belonging to the following classes

Download Notes

Download Handwritten Notes

Unit II

Acids, Bases and Buffers

Buffer equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting isotonicity.

Download Notes

Download Handwritten Notes

Major extra and intracellular electrolytes

Functions of major physiological ions, Electrolytes used in the replacement therapy: Sodium chloride*, Potassium chloride, Calcium gluconate* and Oral Rehydration Salt (ORS), Physiological acid base balance.

Download Notes

Download Handwritten Notes

Dental products

Dentifrices, role of fluoride in the treatment of dental caries, Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol cement.

Download Notes

Download Handwritten Notes

Unit III

Gastrointestinal agents

Acidifiers

Ammonium chloride* and Dil. HCl

Antacid

Ideal properties of antacids, combinations of antacids, Sodium Bicarbonate*, Aluminum hydroxide gel, Magnesium hydroxide mixture

Download Notes

Download Handwritten Notes

Download Handwritten Notes

Cathartics

Magnesium sulphate, Sodium orthophosphate, Kaolin and Bentonite.

Antimicrobials

Mechanism, classification, Potassium permanganate, Boric acid, Hydrogen peroxide*, Chlorinated lime*, Iodine and its preparations.

Download Notes

Download Handwritten Notes

Unit IV

Miscellaneous compounds

Expectorants

Potassium iodide, Ammonium chloride*. Emetics: Copper sulphate*, Sodium potassium tartarate Haematinics: Ferrous sulphate*, Ferrous gluconate
Poison and Antidote: Sodium thiosulphate*, Activated charcoal, Sodium nitrite

Download Notes

Astringents

Zinc Sulphate, Potash Alum

Download Notes

Download Handwritten Notes

Unit V

Radiopharmaceuticals

Radio activity, Measurement of radioactivity, Properties of α, β, γ radiations, Half life, radio isotopes and study of radio isotopes – Sodium iodide I131, Storage conditions, precautions & pharmaceutical application of radioactive substances.

Download Notes

Download Handwritten Notes