Pharmaceutical Chemistry (ER20-12T) Free Notes Download – D. Pharm

 Chapter 1

Introduction to Pharmaceutical chemistry: Scope and objectives

Sources and types of errors: Accuracy, precision, significant figures

Impurities in Pharmaceuticals: Source and effect of impurities in Pharmacopoeial substances, importance of limit test, Principle and procedures of Limit tests for chlorides, sulphates, iron, heavy metals and arsenic.

Download Notes

Chapter 2

Volumetric analysis: Fundamentals of volumetric analysis, Acid-base titration, non-aqueous titration, precipitation titration, complexometric titration, redox titration

Gravimetric analysis: Principle and method.

Download Notes

Chapter 3

Inorganic Pharmaceuticals: Pharmaceutical formulations, market preparations, storage conditions and uses of

Haematinics: Ferrous sulphate, Ferrous fumarate, Ferric ammonium citrate, Ferrous ascorbate, Carbonyl iron
Gastro-intestinal Agents: Antacids :Aluminium hydroxide gel, Magnesium hydroxide, Magaldrate, Sodium bicarbonate, Calcium Carbonate, Acidifying agents, Adsorbents, Protectives, Cathartics
Topical agents: Silver Nitrate, Ionic Silver, Chlorhexidine Gluconate, Hydrogen peroxide, Boric acid, Bleaching powder, Potassium permanganate
Dental products: Calcium carbonate, Sodium fluoride, Denture cleaners, Denture adhesives, Mouth washes
Medicinal gases: Carbon dioxide, nitrous oxide, oxygen

Download Notes

Chapter 4

Introduction to nomenclature of organic chemical systems with particular reference to heterocyclic compounds
containing up to Three rings

Study of the following category of medicinal compounds with respect to classification, chemical name, chemical structure (compounds marked with*) uses, stability and storage conditions, different types of formulations and their popular brand names

Download Notes

Chapter 5

Drugs Acting on Central Nervous System
● Anaesthetics: Thiopental Sodium*, Ketamine Hydrochloride*, Propofol
Sedatives and Hypnotics: Diazepam*, Alprazolam*, Nitrazepam, Phenobarbital*
Antipsychotics: Chlorpromazine Hydrochloride*, Haloperidol*, Risperidone*, Sulpiride*, Olanzapine, Quetiapine, Lurasidone
Anticonvulsants: Phenytoin*, Carbamazepine*, Clonazepam, Valproic Acid*, Gabapentin*, Topiramate, Vigabatrin, Lamotrigine
Anti-Depressants: Amitriptyline Hydrochloride*, Imipramine Hydrochloride*, Fluoxetine*, Venlafaxine, Duloxetine, Sertraline, Citalopram, Escitalopram, Fluvoxamine, Paroxetine

Download Notes

Chapter 6

Drugs Acting on Autonomic Nervous System
Sympathomimetic Agents: Direct Acting: Nor- Epinephrine*, Epinephrine, Phenylephrine,
Dopamine*, Terbutaline, Salbutamol (Albuterol), Naphazoline*, Tetrahydrozoline. Indirect Acting Agents: Hydroxy Amphetamine, Pseudoephedrine. Agents With Mixed Mechanism: Ephedrine, Metaraminol
Adrenergic Antagonists: Alpha Adrenergic Blockers: Tolazoline, Phentolamine
● Phenoxybenzamine, Prazosin. Beta Adrenergic Blockers: Propranolol*, Atenolol*, Carvedilol
Cholinergic Drugs and Related Agents: Direct Acting Agents: Acetylcholine*, Carbachol, And Pilocarpine. Cholinesterase Inhibitors: Neostigmine*, Edrophonium Chloride, Tacrine Hydrochloride, Pralidoxime Chloride, Echothiopate Iodide
Cholinergic Blocking Agents: Atropine Sulphate*, Ipratropium Bromide Synthetic Cholinergic Blocking Agents: Tropicamide, Cyclopentolate Hydrochloride, Clidinium Bromide, Dicyclomine Hydrochloride*

Download Notes

Chapter 7

Drugs Acting on Cardiovascular System
Anti-Arrhythmic Drugs: Quinidine Sulphate, Procainamide Hydrochloride, Verapamil, Phenytoin Sodium*, Lidocaine Hydrochloride, Lorcainide Hydrochloride, Amiodarone and Sotalol
Anti-Hypertensive Agents: Propranolol*, Captopril*, Ramipril, Methyldopate Hydrochloride, Clonidine Hydrochloride, Hydralazine Hydrochloride, Nifedipine,
Antianginal Agents: Isosorbide Dinitrate

Download Notes

Chapter 8

Diuretics: Acetazolamide, Frusemide*, Bumetanide, Chlorthalidone, Benzthiazide, Metolazone, Xipamide, Spironolactone

Download Notes

Chapter 9

Hypoglycemic Agents: Insulin and Its Preparations, Metformin*, Glibenclamide*, Glimepiride, Pioglitazone, Repaglinide, Gliflozins, Gliptins

Download Notes

Chapter 10

Analgesic And Anti-Inflammatory Agents: Morphine Analogues, Narcotic Antagonists; Nonsteroidal Anti- Inflammatory Agents (NSAIDs) – Aspirin*, Diclofenac, Ibuprofen*, Piroxicam, Celecoxib, Mefenamic Acid, Paracetamol*, Aceclofenac

Download Notes

Chapter 11

Anti-Infective Agents
Antifungal Agents: Amphotericin-B, Griseofulvin,
Miconazole, Ketoconazole*, Itraconazole, Fluconazole*, Naftifine Hydrochloride
Urinary Tract Anti-Infective Agents: Norfloxacin, Ciprofloxacin, Ofloxacin*, Moxifloxacin,
Anti-Tubercular Agents: INH*, Ethambutol, Para Amino Salicylic Acid, Pyrazinamide, Rifampicin, Bedaquiline, Delamanid, Pretomanid*
Antiviral Agents: Amantadine Hydrochloride, Idoxuridine, Acyclovir*, Foscarnet, Zidovudine, Ribavirin, Remdesivir, Favipiravir
Antimalarials: Quinine Sulphate, Chloroquine Phosphate*, Primaquine Phosphate, Mefloquine*, Cycloguanil, Pyrimethamine, Artemisinin
Sulfonamides: Sulfanilamide, Sulfadiazine, Sulfamethoxazole, Sulfacetamide*, Mafenide Acetate, Cotrimoxazole, Dapsone*

Download Notes

Chapter 12

Antibiotics: Penicillin G, Amoxicillin*, Cloxacillin, Streptomycin, Tetracyclines: Doxycycline, Minocycline, Macrolides: Erythromycin, Azithromycin, Miscellaneous: Chloramphenicol* Clindamycin

Download Notes

Chapter 13

Anti-Neoplastic Agents: Cyclophosphamide*, Busulfan, Mercaptopurine, Fluorouracil*, Methotrexate, Dactinomycin, Doxorubicin Hydrochloride, Vinblastine Sulphate, Cisplatin*, Dromostanolone Propionate

Download Notes