Reply To: Syndrome Share this post: Share on Twitter Share on Facebook Share on LinkedIn Share on Email Share on WhatsApp Share on Telegram October 14, 2020 at 11:27 am #1352 RameshParticipant A symptom is a manifestation of disease apparent to the patient himself, while a sign is a manifestation of disease that the physician perceives. The sign is objective evidence of disease; a symptom, subjective. Share this post: Share on Twitter Share on Facebook Share on LinkedIn Share on Email Share on WhatsApp Share on Telegram